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5,300 years ago, an injured and starving man from Val Venosta, Italy, fled across an Alpine glacier to escape pursuers. But his enemies caught up with him and with a practiced arrow-shot penetrated his shoulder blade and subclavian artery. Before long, he was dead from blood loss. “Oetzi the Iceman” was found mummified in 1991. On his person were pouches containing mushroom remedies, the oldest known proof in existence of medicinal mushrooms usage.

There is good reason to believe he carried both of these mushrooms along as natural remedies. Whipworm parasite eggs were found in Oetzi’s intestines. Birch polypore mushroom Piptoporus betulinus is a traditional de-worming remedy. The other mushroom in his possession, Tinder fungus (Fomes fomentarius), may have been used to cauterize the wound on his right hand.

Both of these are polypores, so named because they have pores instead of gills underneath. No species of polypore is known to be poisonous. They usually grow on trees, dead or alive.

Polypores are usually considered inedible due to the fact that they are hard and wood-like. But for ancient peoples all across the globe - from China and India to Europe and the Americas - polypore teas and poultices have none-the-less been indispensible allies to human health at least for as long as written and oral traditions can recount.

In North America, some Indian tribes used polypore extracts as remedies against smallpox and other illnesses that arrived with the Europeans. Birch polypore was among these. Other polypores used were Chaga (Inonotus obliquus), Reishi (Ganoderma resinaceum), Turkey tail (Trametes versicolor), and the now threatened species Agarikon (Fomitopsis officinalis).

And as though by no coincidence, Agarikon also holds the distinction as the oldest medicinal mushroom in historic European literature. In 65 B.C., Greek physician Dioscorides recorded it in Materia Medica as a remedy for tuberculosis. More recently, K. Grzywnowics in a 2001 article titled Medicinal Mushrooms in Polish Folk Medicine said Agarikon tea was traditionally considered an elixir for long life and listed historical uses to include lung conditions (coughing, asthma) and rheumatoid arthritis, but also infected wounds and open bleeding.

Up to this point, we’ve only covered the use of medicinal mushrooms in the West. However, their use has been far more widespread in Asia. There are at least three Asian species that would be criminal to leave out of any article on the history of medicinal mushrooms.

First is the polypore Reishi (Ganoderma lucidum), which has been used in China and Japan as a health bestowing mushroom of immortality for at least two millennia. It was first mentioned in the 2,000 year old book Shen Nong’s Herbal Classic. Many ancient wood-carvings and temple engravings in the Orient bear testament to the homage paid to this acclaimed cure-all mushroom.

Next is a mushroom from Tibet known as Cordyceps, a small fungus growing out of the bodies of silk caterpillars. Its first mention was in The Classic Herbal of the Divine Plowman, 200 A.D. Traditionally used as an aphrodisiac, today it’s popular with athletes to improve strength and stamina.

Last but not least is the medicinal mushroom Shiitake, better known as a culinary delight. However, Shiitake is also one of the most research mushrooms for medical properties. Commercial cultivation of Shiitake began about a thousand years ago in China. Medicinal uses include immune enhancement, antibiotic and more. Shiitake extracted Lentinan polysaccharide is approved as an anti-cancer drug in Japan.

Medical research on mushrooms appears to have begun in the late 1960’s in Japan. It gained attention in the West through the research by Dr. Ikekawa, who found that families growing mushrooms had lower cancer-rates than other people in their communities. Since those early days, medical research into mushrooms as grown exponentially and is still increasing. Medicinal mushrooms are continuing to make history.

Note: This article is for informational purpose only. None of the mushrooms mentioned herein have been approved for medicinal use by the FDA. Never use any mushroom medicinally without consulting a licensed medical practitioner.